Gene: [13^/BCS1] breast cancer, ductal, suppressor 1; [BRCD1 BCDS1 ]
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FAG |
A gene with similar biological effect is located in chr 1 (GEM:01p36/BCS2). Inactivation of these genes, e.g. in the phenomenon of loss of heterozygosity, results in ductal brast cancer (BCS1) or breast-ovarian cancer (BCS2)." |
|
HET |
Other breast cancer types may be related to the following genes: GEM:01p36/BCS2; GEM:01q2/SKI; GEM:11p155/ADCR; GEM:21q223/TFF1." |
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REF |
REV,PAT,MUT,FAG "Callahan, Campbell: J Nat Cancer Inst, 81, N23, 1780-1786,
1989 PAT,PHE,FOG "Fraumeni &: Cancer, 36, 364-369, 1975 LIN "Friend SH &: PNAS, 84, N24, 9059-9063, 1987 LOC,LIN,CYG "Lundberg &: PNAS, 84, N8, 2371-2376, 1987 PAT,PHE,FOG "Lynch &: Cancer, 41, 1543-1549, 1978 PAT,LIN,FAG "Rodgers CS &: Cancer Genet Cytogenet, 13, 95-119, 1984 |
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KEY |
onc, horm |
|
CLA |
unknown, basic |
|
LOC |
13 |
|
MIM |
MIM: 211410 |
|
SYN |
BRCD1 BCDS1 |
